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Invited Commentary: Assessing Mechanistic Interaction Between Coinfecting Pathogens for Diarrheal Disease

Scritto da American Journal of Epidemiology - current issues
The interaction estimates from Bhavnani et al. (Am J Epidemiol. 2012;176(5):387–395) are used to evaluate evidence for mechanistic interaction between coinfecting pathogens for diarrheal disease. Mechanistic interaction is said to be ... ... ... continua Aggiungi commento

Infectious Illness in Children Subsequently Diagnosed With Acute Lymphoblastic Leukemia: Modeling the Trends From Birth to Diagnosis

Scritto da American Journal of Epidemiology - current issues
Although there is increasing evidence that immune dysregulation in children who develop acute lymphoblastic leukemia (ALL) is detectable from birth, debate about the role of infectious exposures in infancy continues. With the aim of quantifying c ... ... ... continua Aggiungi commento

Nutritional Risk Factors for Tuberculosis Among Adults in the United States, 1971-1992

Scritto da American Journal of Epidemiology - current issues
The risk of developing tuberculosis (TB) may be related to nutritional status. To determine the impact of nutritional status on TB incidence, the authors analyzed data from the First National Health and Nutrition Examination Survey (NHANES I) Epi ... ... ... continua Aggiungi commento

Integrating Genetic Association, Genetics of Gene Expression, and Single Nucleotide Polymorphism Set Analysis to Identify Susceptibility Loci for Type 2 Diabetes Mellitus

Scritto da American Journal of Epidemiology - current issues
Large-scale genome-wide association studies (GWAS) have identified over 40 genomic regions significantly associated with type 2 diabetes mellitus. However, GWAS results are not always straightforward to interpret, and linking these loci to meanin ... ... ... continua Aggiungi commento

Obesity and All-Cause Mortality Among Black Adults and White Adults

Scritto da American Journal of Epidemiology - current issues
In recent pooled analyses among whites and Asians, mortality was shown to rise markedly with increasing body mass index (BMI; weight (kg)/height (m)²), but much less is known about this association among blacks. This study prospectivel ... ... ... continua Aggiungi commento

Correction of Systematic Bias in Ultrasound Dating in Studies of Small-for-Gestational-Age Birth: An Example From the Iowa Health in Pregnancy Study

Scritto da American Journal of Epidemiology - current issues
The authors examined whether early ultrasound dating (≤20 weeks) of gestational age (GA) in small-for-gestational-age (SGA) fetuses may underestimate gestational duration and therefore the incidence of SGA birth. Within a population-based case ... ... ... continua Aggiungi commento

Age at Last Birth in Relation to Risk of Endometrial Cancer: Pooled Analysis in the Epidemiology of Endometrial Cancer Consortium

Scritto da American Journal of Epidemiology - recent issues
Childbearing at an older age has been associated with a lower risk of endometrial cancer, but whether the association is independent of the number of births or other factors remains unclear. Individual-level data from 4 cohort and 13 case-control ... ... ... continua Aggiungi commento

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