Patologia clinica

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Patologia clinica

Mucinous subtype as prognostic factor in colorectal cancer: a systematic review and meta-analysis

Scritto da Journal of Clinical Pathology
Background Mucinous adenocarcinoma (MAC) of the colorectum has been known and studied for many years. The prognostic significance of this histological subtype remains controversial. The authors reviewed the prognostic significance o ... ... ... continua Aggiungi commento

Quality standards and samples in genetic testing

Scritto da Journal of Clinical Pathology
The most critical performance indicator for medical laboratories is the delivery of accurate test results. In any laboratory, there is always the possibility that random or systematic errors may occur and place human health and welfare at risk. L ... ... ... continua Aggiungi commento

Infantile haemangioma expresses embryonic stem cell markers

Scritto da Journal of Clinical Pathology
Background The origin of infantile haemangioma (IH) remains enigmatic. A primitive mesodermal phenotype origin of IH with the ability to differentiate down erythropoietic and terminal mesenchymal lineages has recently been demonstra ... ... ... continua Aggiungi commento

Clinicopathological significance of podocalyxin and phosphorylated ezrin in uterine endometrioid adenocarcinoma

Scritto da Journal of Clinical Pathology
Background Podocalyxin is an anti-adhesive glycoprotein that has been associated with highly aggressive forms of cancers. Podocalyxin increases the migration and invasive properties of cancer cells through its interaction with ezrin ... ... ... continua Aggiungi commento

Observer agreement comparing the use of virtual slides with glass slides in the pathology review component of the POSH breast cancer cohort study

Scritto da Journal of Clinical Pathology
Aims (1) To compare the use of scanned virtual slide images (virtual microscopy) with glass slides (conventional microscopy) in the assessment of morphological characteristics of breast cancers within the setting of the Prospective ... ... ... continua Aggiungi commento

Adverse reactions to metal debris: histopathological features of periprosthetic soft tissue reactions seen in association with failed metal on metal hip arthroplasties

Scritto da Journal of Clinical Pathology
Aim To describe the histopathology of localised adverse reactions to metal debris (ARMD) seen in association with failed metal on metal (MoM) hip arthroplasties. The nature of aseptic lymphocytic vasculitis associated lesion (ALVAL) ... ... ... continua Aggiungi commento

The neurofibromin 1 type I isoform predominance characterises female population affected by sporadic breast cancer: preliminary data

Scritto da Journal of Clinical Pathology
Aims Neurofibromin 1 (NF1) as a tumour suppressor gene can give rise to several transcripts by an alternative splicing event, generated at least for CELF cofactors. At present, the NF1 isoforms and CELF splicing transcripts in spora ... ... ... continua Aggiungi commento

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